![]() Repetitive neuromodulation protocols can induce long-term neuroplastic changes in brain circuits. Delivering TMS stimuli in a long sequence of pulses (trains or bursts) is called repetitive TMS (rTMS) which has been widely utilized in non-invasive treatments for several neurodegenerative diseases. It has a long history of applications in both neuroscience research and clinical therapies The US food and drug administration (FDA) approved TMS for the treatment of several psychiatric and neurological diseases, such as major depressive disorder and obsessive–compulsive disorder (OCD) and it is under investigation for many other therapies. TMS works by passing a transient current through a treatment coil placed on the patient's head, thus inducing an electric field which safely penetrates the skull. Transcranial magnetic stimulation (TMS) is a non-invasive technique that can activate cortical neurons using electromagnetically induced stimuli. The proposed transcranial magnetic stimulator (TMS) device enables more flexible magnetic stimulus shaping by H-bridge architecture and parallel IGBTs, which can effectively mitigate the current stress on power switches for repetitive treatment protocols. The maximum transferred energy to the treatment coil was measured to be 100.4 J. The maximum positive pulse width in the proposed neurostimulator is up to 600 µs, which is adjustable by the operator at the step resolution of 10 µs. The introduced device enables the production of near-rectangular pulse trains for modulated magnetic stimuli. Experimental results from the circuit characterization show that the proposed circuit is capable of repeatedly generating near-rectangular magnetic pulses and enables the generation of configurable and stable magnetic pulses without causing excessive device stresses. This approach effectively reduces the current stress on the power switches while maintaining a simple structure using a single DC source and energy storage capacitor. To this end, we develop a parallel- Insulated-gate bipolar transistors (IGBT)-based magnetic pulse generator utilizing the H-bridge architecture. ![]() In this study we present the new power electronic circuit implementation to create the arbitrary near-rectangular electromagnetic pulse. ![]()
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